摘要：

Biol. active exts. of the Caribbean sponge A. conifera have yielded, in exhaustive studies, the diacetate salts of seven new bromopyrroles, as well as that of the known debromooroidin dimer sceptrin. These compds. were found to be antiviral and antibacterial and were active in barnacle settlement and biochem. prophage induction assays. The structures assigned were based on spectroscopic comparisons to sceptrin and two-dimensional NMR data. Synthetic bromopyrroles were used to verify bromine substitution patterns. The oxysceptrins are characterized by their aminoimidazolinone group, the ageliferins, by a unique cyclohexene-based skeleton

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