摘要：

Objective: To study the expression of two isoforms(i.e.livin α and livin β) of livin,a novel inhibitor of apoptosis protein(IAP) family member,in gastric cancer tissues.Methods: The expression levels of livin mRNA in gastric cancer tissue were detected by the method of reverse transcription polymerase chain reaction(RT-PCR).Results: The positive rate of livin expression in 48 cases of gastric cancer was 58.7%,while no or little livin expression was detected in corresponding para-cancerous tissues.Conclusions: The two livin isoforms express in gastric cancer tissues.As molecular marker of gastric cancer,livin may be a new target of therapy for gastric cancer.

展开