Enzyme Inhibitors from Marine Invertebrates
摘要：
Marine invertebrates are rich sources of small molecules with unique chemical skeletons and potent bioactivities. Historically, such compounds were discovered mainly through the use of assays for phenotype-oriented activities, such as cytotoxicity or antimicrobial effects. More recently, target-oriented searches for bioactive substances, as exemplified by enzyme inhibitors, have become much more common, given a growing need for small-molecule inhibitors essential for studies of complex processes at the interface of chemistry and biology. In this review, selected enzyme inhibitors from marine invertebrates are presented.
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DOI：
10.1021/np060600x
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年份：
2007
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来源期刊
Journal of Natural Products
2007 Apr;
引用走势
2011
被引量：28
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