摘要：

An interesting series of heterocyclic base adducts of copper(II) complexes have been synthesised by the reaction of copper(II) acetate with salicylaldehyde N(4)-phenylthiosemicarbazone in presence of heterocyclic bases like pyridine (py), piperidine (pip), β / γ -picoline ( β / γ -pic), 1,10-phenanthroline (phen) and 2,2′-bipyridine (bipy). IR, electronic, 1 H and 13 C NMR spectra of the thiosemicarbazone, as well as IR, electronic and EPR spectra of the complexes have been obtained. Based on EPR studies spin Hamiltonian and bonding parameters have been calculated. The g values, calculated for all the complexes in frozen DMF, indicate the presence of the unpaired electron in the d x 2 y 2 orbital. The metal-ligand bonding parameters evaluated showed strong in-plane sigma and in-plane π bonding. The magnetic and spectroscopic data indicate a square planar geometry for the four-coordinate and a distorted square pyramidal for five-coordinate complexes. From cyclic voltammetric data reversible copper(II)/copper(I) couples are observed for these complexes. The thiosemicarbazone and its copper(II) complexes show growth inhibitory activity against human pathogenic bacteria Salmonella typhi , Shigella dysentariae , non-coagulace Staphylococcus , Photobacterium sp. and Staphylococcus aureus and plant pathogenic fungi Rhizoctonia , Collectotrichium and Aspergillus sp.

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