Concise Syntheses of (+)-Macrosphelides A and B
摘要：
Unified and highly convergent total syntheses of (+)-macrosphelides A and B are described. Key features of the syntheses include (1) concise synthesis of the optically active δ-hydroxy-γ-keto α,β-unsaturated acid fragment via the direct addition of a trans-vinylogous ester anion equivalent to the readily available Weinreb amide and (2) facile construction of the 16-membered macrolide core of the macrosphelide series via an intramolecular nitrile-oxide cycloaddition (INOC).
展开
关键词：
CELL-CELL ADHESION MACROSPHELIDE-A ABSOLUTE STEREOSTRUCTURES (+)-BREFELDIN-A ESTERIFICATION INHIBITORS MACROLACTONIZATION REDUCTION MOLECULE STRATEGY
DOI：
10.1021/ol0508429
被引量：
年份：
2005
国家科技图书文献中心
(权威机构)
ACS
ACS
(全网免费下载)
掌桥科研
万方医学
查看更多
dx.doi.org
NCBI
NCBI
Europe PMC
ResearchGate
EBSCO
mendeley.com
pubfacts.com
deepdyve.com
onacademic.com
ACS
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
