Different surface glycoprotein patterns on human T-, B- and leukemic-lymphocytes
摘要：
We have labeled the exposed surface glycoprotein of human blood T- and B-lymphocytes and cells from patients with chronic lymphocytic leukemia by the galactose oxidase-tritiated sodium borohydride method. The labeled glycoproteins were separated by polyacrylamide slab gel electrophoresis and visualized by autoradiography. The T- and B-lymphocytes show different and characteristic surface glycoprotein patterns. The surface glcoprotein patterns of the leukemic cells differ from those of normal, non-malignant lymphocytes. A relationship between the altered surface glycoprotein pattern of leukemic cells and the expression of leumemiaassociated antigens is discussed.
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DOI：
10.1002/ijc.2910170107
被引量：
年份：
1976
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