A combinational optimization method for efficient synthesis of tetramethylpyrazine by the recombinant Escherichia coli
摘要：
Acetoin (3-hydroxy-2-butanone), an extensively-used food spice and bio-based platform chemical, is usually produced by chemical synthesis methods. With increasingly requirement of food security and environmental protection, bio-fermentation of acetoin by microorganisms has a great promising market. However, through metabolic engineering strategies, the mixed acid-butanediol fermentation...
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DOI：
10.1016/j.bej.2017.10.010
被引量：
年份：
2018
Elsevier
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