Antibacterial benzothiazole derivatives

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14

公开/公告日期:

May 26, 2016

发明人:

C SchmittJP SurivetG ChapouxA MirreJL Specklin

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摘要:

The invention relates to antibacterial compounds formula (I) wherein R 1 is the group M, whereby M is one of the groups M A and M B represented below wherein A is a bond or C≡C; R 1A is H or halogen; R 2A is H or halogen; R 3A is H, alkoxy, hydroxyalkoxy, hydroxyalkyl, dihydroxyalkyl, 2-hydroxyacetamido, substituted cycloprop-1-yl or substituted oxetan-3-yl; and R 1B is hydroxyalkyl, dihydroxyalkyl, aminoalkyl, dialkylaminoalkyl, substituted cycloprop-1-yl, substituted cyclobutan-1-yl, substituted oxetan-3-yl, 3-hydroxythietan-3-yl, substituted azetidin-3-yl, trans -( cis -3,4-dihydroxy)-cyclopent-1-yl, 3-hydroxymethylbicyclo[1,1,1]pentan-1-yl, 4-hydroxytetrahydro-2 H -pyran-4-yl, (3R,6S)-3-aminotetrahydro-2 H -pyran-6-yl, piperidin-4-yl or 1-(2-hydroxyacetyl)piperidin-4-yl; and salts thereof.

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