摘要：

Technique; for the COX-2-selective inhibitor drug for preparing oral instant composition; the process includes (a) the wet particulate drug of step and adhesive includes sugared high formability; (2) the step of being blended and drug sugar poor-compactibility, wherein appearance or simulatenously are formed in any order to lead to particle by above-mentioned steps (one) and (two). The process has been optionally incorporated into method and has inhibited reunion drug, such as addition wetting agent. Optionally, which further comprises the step of (three) are blended, the particle and at least one lubricant, sweetener and flavoring agent, and to form tableting blend, the compression tableting blend of Step d is to form oral instant-dissolving tablet. Composition is also provided, this technique is passed through.

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