摘要：

Twelve normally menstruating women were stimulated with (1) menopausal gonadotropins (hMG) containing follicle-stimulating hormone (FSH) and luteinizing hormone (LH) and (2) FSH only to induce growth of multiple follicles for oocyte retrieval. Maturation of the follicles and presumptively the oocytes was assessed by daily serum () values, the response of the vaginal epithelium, and cervical mucus. The growth and number of follicles were measured by ultrasound daily. chorionic gonadotropin was administered as a surrogate LH surge. The hMG cycles were compared with the FSH-only cycles in relation to serum and , , transfer, and rates. Five of eight cycles adequately stimulated with FSH only resulted in successful . FSH without additional LH can initiate and maintain function and allow to proceed up to the terminal maturation, which is associated with the LH surge. The effect of LH may be to hasten follicular atresia in the developing cohort of follicles.

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