Fatal carcinoma of the thyroid: histology, metastases, and causes of death.
摘要:
The lethal potential of thyroid carcinoma is emphasized by this study of 54 autopsied cases. The anaplastic cancers rapidly produced death by extensive local and metastatic disease, while the well-differentiated forms were associated with more protracted courses, and death from local disease was less common. The ominous significance of the infrequent conversion of well-differentiated papillary or follicular carcinoma to an anaplastic variant is noted. Sites of metastases are analyzed both for the entire series and individually for each histologic type of tumor. The data presented in this report emphasize the fact that the histologic differences among the various types of thyroid carcinoma signify important clinical differences as well, and point out the need for individualization of therapy in each case.
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DOI:
10.1002/1097-0142(197004)25:43.0.CO;2-P
被引量:
年份:
1970
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