Traditional Chinese lipid-lowering agent red yeast rice results in significant LDL reduction but safety is uncertain – A systematic review and meta-analysis
摘要：
We systematically reviewed and meta-analyzed the effectiveness and safety of red yeast rice extract for cardiovascular risk reduction.We analyzed 20 randomized trials on 6663 patients.The placebo-subtracted reduction of LDL was 0.68 till 1.44mmol/l with a pooled estimate of1.02mmol/L (95% CI1.20;0.83).The incidence of kidney injury and liver abnormalities was <5% in both RYR and control groups. The rate of myopathy did not differ between RYR and control groups.The design and reporting of adverse events were in most studies insufficient to make a firm judgement on the safety of red yeast rice extract.
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DOI：
10.1016/j.atherosclerosis.2015.04.004
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年份：
2015
Elsevier
Elsevier
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万方医学
Semantic Scholar
掌桥科研
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