Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies.

来自 EBSCO

阅读量:

74

作者:

WenzelSallyWilbrahamDarrenFullerRickGetzE BurmeisterLongphreMalinda

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摘要:

This article reports on a clinical trial that looked at the effect of an interleukin-4 variant on last phase asthmatic response. Increases in Th2- cytosine concentrations have been seen in atopic asthma. It is thought that interleukin 4 and interleukin 13 have a role in the physiological response. The study was conducted to assess the therapeutic value of pitrakinra in the treatment of atopic asthma. The study found that treatment forcing the inhibition of interleukins 4 and 13 in the lung could lessen the symptoms of asthma.

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被引量:

563

年份:

2007

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2014
被引量:77

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