Adenosine receptors: Target sites for drugs. J. Med. Chem. 25, 197-207
摘要:
A xanthine amine congener (XAC), an amine-functionalized derivative of 1,3-dipropyl-8-phenylxanthine, is an antagonist ligand for A2 adenosine receptors of human platelets. XAC inhibited 5'-N-ethylcarboxamidoadenosine (NECA)-induced stimulation of adenylate cyclase activity with a KB of 24 nM. [3H]XAC exhibits saturable, specific binding with a Kd of 12 nM and a Bmax of 1.1 pmol/mg protein at...
展开
DOI:
10.1021/jm00345a001
被引量:
年份:
1982
通过文献互助平台发起求助,成功后即可免费获取论文全文。
请先登入
相似文献
参考文献
引证文献
来源期刊
Journal of Medicinal Chemistry
1982/04/01
引用走势
1990
被引量:25
辅助模式
0
引用
文献可以批量引用啦~
欢迎点我试用!