摘要：

This invention relates to matrix metalloproteinase (MMP) inhibiting compounds of the formula: ##STR1## where Ris C-Calkyl, straight or branched and optionally substituted by halogen, hydroxy, C-Calkoxy, amino, carboxyl, C-Calkoxycarbonyl, carboxamido, nitrile, mono- or di-(C-C)alkylamino, thio, C-Calkylthio, aryl, --Oaryl or --OCHaryl where aryl is optionally substituted with C-Calkyl, C-Calkoxy, carboxy, halogen, cyano, nitro, carboxamido, or hydroxy; and C-Calkanesulfonyloxy. Ris α-OH or β-OH and Ris H or Rand Rtogether are carbonyl; the chemical intermediates; and processes for the preparation of these compounds and the intermediates thereto.

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