Increased interleukin 1 beta in human skeletal muscle after exercise.
摘要：
Interleukin 1 beta () is released from blood monocytes and related cells in response to infectious or inflammatory stimuli. Although is elevated in the for only a few hours after an acute inflammatory challenge or exercise, it has been proposed to mediate anabolic and catabolic processes that can last for several days. In this report, eccentric exercise was used as a noninfectious inflammatory stimulus. was found in muscle tissue up to 5 days after exercise using specific immunohistochemical tissue staining. Increased immunoreactivity was observed in muscle tissue from four subjects who performed the exercise, but not in tissue obtained at the same time intervals from two subjects who did not exercise. Little immunohistochemical evidence of interleukin-1 alpha or alpha was observed before or after exercise. These results implicate in the metabolic adaptations of muscle tissue, which occur in response to noninfectious stresses.
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DOI：
doi:10.1111/j.1748-1716.1989.tb08714.x
被引量：
年份：
1989
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