Highly Enantioselective Thiourea‐Catalyzed Nitro‐Mannich Reactions

来自 Wiley

阅读量:

49

作者:

TP YoonEN Jacobsen

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摘要:

Approaching “privileged” status? A new and highly effective enantioselective catalyst for the nitro‐Mannich reaction was identified by modification of thiourea‐based Strecker catalysts (see scheme). Products are obtained in high enantiomeric purity and up to 16:1 diastereoselectivity.

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DOI:

10.1002/anie.200461814

被引量:

930

年份:

2004

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