Organization of lipids in the plasma membranes of malignant and stimulated cells: a new model
摘要：
Neutral lipids make up about 6% of the lipid content of plasma membranes from malignant cells. Magnetic resonance spectroscopy (MRS) identifies this neutral lipid as predominantly triglyceride which is not in bilayer form. A new structural model is proposed whereby neutral lipid domains are intercalated with the bilayer lipid of the plasma membrane. A functional role for these neutral lipid domains is also proposed based on plasma membrane alterations which occur with cellular stimulation, with the acquisition of resistance to anti-cancer drugs, and in metastatic cells.
展开
关键词：
Animals Humans Rats Tumor Cells, Cultured Cell Membrane Membrane Lipids Lipid Bilayers Magnetic Resonance Spectroscopy Neoplasms Models, Biological
DOI：
10.1016/0968-0004(88)90145-4
被引量：
年份：
1988
通过文献互助平台发起求助，成功后即可免费获取论文全文。
相似文献
参考文献
引证文献
引用走势
辅助模式
引用
文献可以批量引用啦~
欢迎点我试用！
