摘要：

We report a case of metachronous and multiple mucosa-associated lymphoid tissue (MALT) lymphomas of the cecum and rectum. A 67-year-old male was first admitted to another hospital. Colonoscopy revealed a flat elevated lesion in the cecum and rectum. Endoscopic mucosal resection was performed for the diagnostic purpose. The histopathology of the resected specimens demonstrated a MALT lymphoma with the depth of invasion being at the deep submucosal layer and the cut-end was free of lymphoma. Then he was referred to our hospital and followed up closely by endoscopy, but no relapse of these lesions occured. However, 14 months after previous lesions, a new lesion appeared in the rectum and the depth of invasion was diagnosed as the muscular propria (MP) by endoscopic ultrasonography (EUS). We performed operation in October 2002. According to the General Rule for Clinical and Pathological Studies on Cancer of the colon, rectum and anus, we diagnosed the lesion as SM, N1(+), M(-) stage I. If EMR is the first choice of therapy, a close follow-up should be performed. The long term follow-up is necessary to assesse the prognosis.

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