Do inhibitory immune receptors play a role in the etiology of autoimmune disease?
摘要:
Individual inhibitory immune receptor knockout mice often have an autoimmune phenotype.Disturbed inhibitory receptor expression and function is found in autoimmune patients.GWAS identifies only a few inhibitory receptor genes as risk factors for autoimmunity.GWAS links downstream effectors such as CSK and LYP to autoimmunity.
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DOI:
10.1016/j.clim.2013.11.007
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年份:
2013
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来源期刊
Clinical Immunology
2013/11/19
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2013
被引量:17
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