Hypoalgesia and altered inflammatory responses in mice lacking kinin B1 receptors.

Describes kinin receptors B1 and B2. Generation of kinin B1-receptor knockout mice; Blood pressure; Inflammation; Analgesic nature of the kinin receptors i...

Pesquero，Joao，B.，... - 《Proceedings of the National Academy of Sciences of the United States of America》

Hyperalgesia, anxiety, and decreased hypoxic neuroprotection in mice lacking the adenosine....

Explores the effect of the absence of adenosine A[sub 1] receptor in mice. Decrease in neuronal activity; Influence on synaptic activity.

Johansson，Bjorn，Halldner，... - 《Proceedings of the National Academy of Sciences of the United States of America》

Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia

Although the N-arachidonoyl ethanolamine (anandamide) binds to cannabinoid receptors and has been implicated in the suppression of pain, its rapid cataboli...

A Lichtman - 《Pain》

Mice lacking fatty acid amide hydrolase exhibit a cannabinoid receptor-mediated phenotypic hypoalgesia

Although the N-arachidonoyl ethanolamine (anandamide) binds to cannabinoid receptors and has been implicated in the suppression of pain, its rapid cataboli...

Aron H Lichtman and Christopher C Shelton and Tushar Advani and Benjamin F Cravatt - 《Pain》

Pain sensitivity and opioid activity in genetically and experimentally hypertensive rats

Naloxone reversed this hypoalgesia in both experimentally and genetically hypertensive rats while it did not affect blood pressure in any rat-type tested. ...

N Zamir，R Simantov，M Segal - 《Brain Research》

The relationship between resting blood pressure and acute pain sensitivity: effects of chronic pain and alpha-2 adrenergic blockade

This study tested for alpha-2 adrenergic mediation of the inverse relationship between resting blood pressure and acute pain sensitivity in healthy individ...

S Bruehl，OY Chung，L Diedrich，... - 《Journal of Behavioral Medicine》

Reduced response to the formalin test and lowered spinal NMDA glutamate receptor binding in adenosine A2A receptor knockout mice

Adenosine is a neuromodulator with complex effects on pain pathways. Mice lacking the adenosine A 2A receptor are hypoalgesic, and have altered analgesic r...

MJ Hussey，GD Clarke，C Ledent，... - 《Pain》

Adenosine A2A receptor deficient mice are partially resistant to limbic seizures

Ledent C, Vaugeois J-M, Schiffmann SN et al (1997) Aggressiveness, hypoalgesia and high blood pressure in mice lacking the adenosine A2A receptor. Nat...

ME Yacoubi，C Ledent，M Parmentier，... - Naunyn-Schmiedeberg's Archives of Pharmacology