NANOPARTICULATE CLOPIDOGREL FORMULATIONS
申请(专利)号:
KR20077028536
申请日期:
2007-12-06
公开/公告号:
KR20080008403A
公开/公告日期:
2008-01-23
申请(专利权)人:
ELAN PHARMA INTERNATIONAL LTD.
被引量:
摘要:
The present invention is directed to compositions comprising a nanoparticulate clopidogrel, or a salt or derivative thereof, having improved bioavailability. The nanoparticulate clopidogrel particles of the composition have an effective average particle size of less than about 2000 nm and are useful in the prevention and treatment of pathologies induced by platelet aggregation. The clopidogrel particles may also be formulated as a controlled release polymeric coating or matrix drug delivery system.
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