摘要：

本发明涉及磷酸二酯酶(PDE)Ⅳ型的选择性抑制剂4-取代儿茶酚二醚化合物。 The present invention relates to phosphodiesterase (PDE) Ⅳ selective inhibitors of type 4-substituted catechol diether compounds. 本发明的化合物用于抑制PDEIV以及治疗艾滋病、哮喘、关节炎、支气管炎、慢性阻滞性呼吸道疾病、牛皮癣、过敏性鼻炎、 皮炎和其它炎症疾病。 The compounds of the invention are used to inhibit PDEIV and treatment of AIDS, asthma, arthritis, bronchitis, chronic retardance respiratory disease, psoriasis, allergic rhinitis, dermatitis and other inflammatory diseases. 本发明也涉及含有这些化合物的药物组合物。 The present invention also relates to pharmaceutical compositions containing these compounds.

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