Reovirus messenger RNA contains a methylated, blocked 5\"-terminal structure: m7G(5\")ppp(5\")GmpCp-
摘要:
Reovirus mRNA synthesized in vitro by the virus-associated RNA polymerase in the presence of S-adenosylmethionine contains blocked, methylated 5'-termini with the structure, m-7G(5')ppp(5')G-MpCp. The functional significance and possible mechanism of formation of this novel 5'-5' terminal nucleotide linkage are discussed.
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DOI:
10.1073/pnas.72.6.2468-a
年份:
1975
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