摘要：

And a bioavailability of clopidogrel is improved, the invention is directed to a composition comprising a salt or derivative thereof or a blend of aspirin and clopidogrel nanoparticles. Nanoparticulate clopidogrel particles of the composition, and have an effective average particle size of less than about 2000nm, aspirin nanoparticulate particles are useful in the prevention and treatment of conditions induced by platelet aggregation optionally. In addition, aspirin and clopidogrel particles can also be formulated as a matrix drug delivery systems or controlled release polymer coating.

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