DIHYDROAZAMACROSPHELIDES : SYNTHESIS AND APOPTOSIS INDUCING ACTIVITIES
摘要:
Dihydroazamacrosphelides, which were aza-analogues of 3-epi macrosphelide L, were prepared according to ring-closing metathesis strategy. Their biological assay revealed that the oxidized diketo-analogues showed stronger apoptosis inducing activity than their dihydroxy precusors.
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关键词:
Macrosphelide Aza-Analogue Apoptosis Inducing Activity Ring-Closing Metathesis Strategy Macrolactam
DOI:
10.3987/com-11-12357
被引量:
年份:
2011
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