Lung Infection Caused by Mycobacterium riyadhense Confused with Mycobacterium tuberculosis: The First Case in Korea
摘要：
A slowly growing, non-chromogenic mycobacterial strain was isolated from sputum and bronchial lavage fluid samples of a patient presenting with productive cough, blood-tinged sputum, low-grade fever, and weakness. A positive acid-fast bacilli sputum smear result prompted the initiation of an anti-tuberculosis regimen. Multiplex real-time PCR showed a negative result forMycobacterium tuberculosiscomplex and a positive result for nontuberculous mycobacteria. The DNA chip test confirmed this organism as a member of the genusMycobacterium, but could not specify the species. Interestingly, the mycolic acid patterns obtained by HPLC nearly overlapped with those ofM. simulans. The sequences of theMycobacterium16S rRNA gene and 16S-23S internal transcribed spacer region were unique and were found to have 100% similarity with those ofM. riyadhense. After a review of the literature, we report this case as the first Korean case ofM. riyadhenselung infection.
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DOI：
10.3343/alm.2012.32.4.298
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年份：
2012
掌桥科研
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万方医学
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