Primary ciliary dyskinesia: diagnosis and standards of care.

Primary ciliary dyskinesia (PCD) is characterized by disease of the upper and lower respiratory tract, in association with visceral mirror image arrangemen...

 - 《European Respiratory Journal》

Longitudinal study of lung function in a cohort of primary ciliary dyskinesia

Patients with () have pronounced stasis of their respiratory and therefore recurrent lower airway , which raises concerns for the of lung function. Twenty ...

A Ellerman，H Bisgaard - 《European Respiratory Journal》

Clinical and genetic aspects of primary ciliary dyskinesia/Kartagener syndrome

Primary ciliary dyskinesia is a genetically heterogeneous disorder of motile cilia. Most of the disease-causing mutations identified to date involve the he...

MW Leigh，JE Pittman，JL Carson，... - 《Genetics in Medicine》

The dyskinetic cilia syndrome. Ciliary motility in immotile cilia syndrome.

Ciliary motility was studied in three patients with Kartagener syndrome who had previously been found to have absent nasal and pulmonary mucociliary transport and missing dynein arms in nasal cilia. A video system was used to record move...

CM Rossman，JB Forrest，RMKW Lee，... - 《Chest》

Smoking Is Associated with Shortened Airway Cilia.

Background: Whereas cilia damage and reduced cilia beat frequency have been implicated as causative of reduced mucociliary clearance in smokers, theoretica...

Leopold，L Philip，O'Mahony，... - 《Plos One》

Erratum: A viscoelastic traction layer model of muco-ciliary transport (Bulletin of Mathematical Biology DOI: 10.1007/s11538-005-9036-x)

We discuss in detail techniques for modelling flows due to finite and infinite arrays of beating cilia. An efficient technique, based on concepts from previous 'singularity models' is described, that is accurate in both near and far-fiel...

DJ Smith，EA Gaffney，JR Blake，...

Muco-ciliary transport: Effect of mucus viscosity, cilia beat frequency and cilia density

We discuss in detail techniques for modelling flows due to finite and infinite arrays of beating cilia. An efficient technique, based on concepts from previous 'singularity models' is described, that is accurate in both near and far-fiel...

Lee，W.，L.，... - 《Computers & Fluids》

Computer Simulations of Particle Deposition in the Developing Human Lung

An age-dependent theoretical model has been developed to predict PM dosimetry in children''s lungs. Computer codes have been written that describe the dime...

CJ Musante，TB Martonen - 《Air Repair》

Three-dimensional numerical simulations of human pulmonary cilia in the periciliary liquid layer by the immersed boundary method

The airway surface liquid of human respiratory system consists of two layers which are the innermost watery periciliary liquid layer (PCL) and the uppermos...

PG Jayathilake，Z Tan，DV Le，... - 《Computers & Fluids》

Ciliated Epithelium in Respiratory Diseases

Background: The ciliated respiratory epithelium that covers the surface of human airway forms an immunologically active natural barrier to invasion and injury by inhaled noxious agents. Ciliary dysfunction and or epithelial damage compro...

C O'Callaghan，B Thomas