The detection of various nitrosamines in the hepatocyte primary culture/DNA repair test
摘要：
Summary Evaluation of 6 carcinogenic nitrosamines in the hepatocyte primary culture/DNA repair test revealed that all were active. Three non-carcinogenic analogs were negative. This sensitivity to nitrosamines, together with considerations concerning the metabolic capability and end point of this assay, indicates that it will be a useful addition to screening batteries that include bacterial mutagenesis assays.
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关键词：
DMSO dimethylsulfoxide dimethylsulfoxide HPC hepatocyte primary hepatocyte primary NNK 4-(methyl- N-nitrosoamino)-1-(3 pyridyl)-1-butanone 4-(methyl- N-nitrosoamino)-1-(3 pyridyl)-1-butanone NNN nitrosonornicotine, culture nitrosonornicotine, culture TdR thymidine thymidine
DOI：
10.1016/S0304-3835(79)80034-8
被引量：
年份：
1979
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