摘要：

A molecular hybridization strategy has been utilized for the synthesis of novel 1'-indanolfused 3-oxindoles via a regioselective domino Michael/Aldol reaction of 3-ylideneoxindoles with malononitrile or cyanacetate ethyle,using toluene as the solvent. The yields and dr were 73% ~ 90% and10/1,respectively. The structures were characterized by1 H NMR,13 C NMR and HR-MS( ESI-TOF).

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