摘要：

An open epicutaneous test (OET) is proposed for the detection of Skin Irritation and Contact Hypersensitivity induced in Guinea Pigs. Thirty-two compounds described in the literature as being Allergenic for man were tested in the guinea pig by the OET technique, and for the purpose of comparison, by three other techniques, namely the Draize Test (DT), the Maximization Test (MT) and a test with Freund's Complete Adjuvant (FCAT). In the OET, a high degree of correlation was found between the allergenicity of the tested compounds for the guinea pig and for man.

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