Tissue engineered liver constructs

阅读量:

19

申请(专利)号:

US11086547

申请日期:

20050321

公开/公告号:

US20050249816A1

公开/公告日期:

20051110

申请(专利权)人:

Anthony Atala Mohummad Minhaj Siddiqui

发明人:

A AtalaMM Siddiqui

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被引量:

241

摘要:

The invention is directed to methods for producing a decellularized liver or part of an liver. A decellularized organ is produced using an isolated liver mechanically agitated to remove cellular membranes surrounding the isolated liver without destroying the interstitial structure of the liver. After the cellular membrane is removed, the isolated liver is exposed to a solubilizing fluid that extracts cellular material without dissolving the interstitial structure of the liver. A washing fluid is used to remove the solubilized components, leaving behind a decellularized liver.

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引用走势

2007
被引量:21

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