摘要：

Objectives: Evidence-based medicine allows the best available external clinical evidence from systematic literature rese - arch to be graded in order to determine the strength of its recommendation. This guideline aims to assist physicians and healthprofessionalsinclinicaldecisionsrelatedtoprostatecancertreatment,particularlyinurology,clinicaloncologyand radiotherapy. Methods: The publications used as information sources were obtained from structured data search in electronic databa - ses, such as CENTRAL (Cochrane Central Register of Controlled Clinical Trials) and MEDLINE (online). Each item of this guideline derived from an original question which was distributed to the participants. Search strategies were prepared to select the studies presenting the best methodological quality, according to predefined levels of evidence. Results: All the recommendations were followed by a level of evidence (LE) and a degree of recommendation (DR). We used a formal ranking system to help the reader to judge the strength of the evidence behind the results published in support of each recommendation. Conclusions: The existing parameters should be viewed as guidelines of conduct. The final trial on which the clinical procedure or treatment plan is most suitable for a particular patient should be done by a physician, who should discuss the available treatment options with the patient according to the diagnosis.

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