Acanthus ebracteatus leaf extract provides neuronal cell protection against oxidative stress injury induced by glutamate

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38

作者:

A PrasansuklabT Tencomnao

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摘要:

BackgroundAcanthus ebracteatus (AE), an herb native to Asia, has been recognized in traditional folk medicine not only for its antioxidant properties and various pharmacological activities but also as an ingredient of longevity formulas. However, its anti-neurodegenerative potential is not yet clearly known. This work aimed to evaluate the protective effect of AE leaf extract against glutamate-induced oxidative damage in mouse hippocampal HT22 cells, a neurodegenerative model system due to a reduction in glutathione levels and an increase in reactive oxygen species (ROS).

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DOI:

10.1186/s12906-018-2340-4

年份:

2018

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