Optical and electrical methods and apparatus for molecule detection
申请(专利)号：
WO1993US03829
申请日期：
1993-04-23
公开/公告号：
WO9322678A2
公开/公告日期：
1993-11-11
申请(专利权)人：
MASSACHUSETTS INSTITUTE OF TECHNOLOGY;BAYLOR COLLEGE OF MEDECINE;HOUSTON ADVANCED RESEARCH CENTER
被引量：
摘要：
A method and apparatus are disclosed for identifying molecular structures within a sample substance using a monolithic array of test sites formed on a substrate upon which the sample substance is applied. Each test site includes probes formed therein to bond with a predetermined target molecular structure or structures. A signal is applied to the test sites and certain electrical, mechanical and/or optical properties of the test sites are detected to determine which probes have bonded to an associated target molecular structure.
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