摘要：

RationaleDividing cells can be detected in the live brain by positron emission tomography or optical imaging. Here we apply proton magnetic resonance spectroscopy (¹HMRS) and a widely used spectral fitting algorithm to characterize the effect of increased neurogenesis after electroconvulsive shock in the live rodent brain via spectral signatures representing mobile lipids resonating at ~1.30 ppm. In addition, we also apply the same ¹HMRS methodology to metabolically profile glioblastomas with actively dividing cells growing in RCAS-PDGF mice.

展开