Palladium-catalyzed preparation of Weinreb amides from boronic acids and N-methyl-N-methoxycarbamoyl chloride.
摘要:
A simple protocol for the synthesis of Weinreb benzamides and alpha,beta-unsaturated Weinreb amides through a palladium-catalyzed cross-coupling reaction between organoboronic acids and N-methoxy-N-methylcarbamoyl chloride has been developed. The method is also applicable to the use of potassium organotrifluoroborates.
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关键词:
carboxylic amides (benzene compounds carboxylic amides (acyclic compounds cyclohexane derivatives general (heterocyclic compounds
DOI:
10.1002/chin.201023072
被引量:
年份:
2010
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