摘要：

The Reformatsky reagents derived from ethyl bromoacetate and tert-butyl bromoacetate add cleanly, in high yield, and with good diastereoselectivity to N-tert-butanesulfinyl aldimines and ketimines. Importantly, this reaction scales well (>50 mmol), and affords products upwards of 70% yield over three steps, starting from commercially available N-tert-butanesulfinamide, aldehydes, and ketones.

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