Initial Drug Resistance and Tuberculosis Treatment Outcomes: Systematic Review and Meta-analysis
摘要：
Optimizing tuberculosis treatment outcomes is increasingly difficult as drug-resistant tuberculosis becomes more common. Lew and colleagues reviewed 22 trials and 7 cohort studies that involved 14 333 new tuberculosis cases. Poor outcomes were associated with drug-resistant organisms at the outset of therapy and with treatment that did not reflect drug-susceptibility testing. Failure or relapse rates were 35% to 40% for patients who received rifampin for 2 months and 20% for patients who received rifampin for 6 months. Settings that do not do susceptibility testing before tuberculosis treatment can expect poor outcomes.
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年份：
2008
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