ChemInform Abstract: STUDIES ON THE CONFORMATIONAL MOBILITY OF ARACHIDONIC ACID. FACILE MACROLACTONIZATION OF 20-HYDROXYARACHIDONIC ACID
摘要:
20-Hydroxyarachidonic acid is converted to the corresponding 21-membered lactone via the 2-thiolpyridine ester in > 90% yield and at a rate which is approximately 100 times that for the saturated analog, evidence that only a modest increase in free energy is required to bring the ends of the chain into proximity.
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DOI:
10.1016/S0040-4039(00)81320-9
被引量:
年份:
1983
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来源期刊
Tetrahedron Letters
1983
引用走势
2010
被引量:110
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