Parkinson's disease-associated protein Parkin: an unusual player in cancer
摘要：
The mutation of the Parkin gene is a cause of familial Parkinson's disease.A growing body of evidence suggests that Parkin also functions as a tumor suppressor.Parkin is an ubiquitin E3 ligase,and plays important roles in a variety of cellular processes implicated in tumorigenesis,including cell cycle,cell proliferation,apoptosis,metastasis,mitophagy and metabolic reprogramming.Here we review the role and mechanism of Parkin in cancer.
展开
DOI：
10.1186/s40880-018-0314-z.
年份：
2018
Springer
(全网免费下载)
国家科技图书文献中心
(权威机构)
维普期刊专业版
ResearchGate
学术范
(全网免费下载)
查看更多
学术范
Springer Verlag
(全网免费下载)
通过文献互助平台发起求助，成功后即可免费获取论文全文。
请先登入
相似文献
参考文献
引证文献
辅助模式
0
引用
文献可以批量引用啦~
欢迎点我试用！
