摘要：

A new route to the indolo[2,3-a]quinolizidin-2-one ring system is reported. It is based on the elaboration of the C ring in the key step by cyclization upon the indole 3-position of an N-substituted 2-(2-indolyl)-4-piperidone derivative. This cyclization was efficiently accomplished by treatment of the sulfonylated indole alcohol 6 with potassium tert-butoxide.

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