摘要：

100 patients with unstable angina enrolled in our hospital from October 2015 to October 2016 were randomly divided into two groups (n=50).Patients in the control group were treated with aspirin.Patients in the observation group were treated with clopidogrel combined with aspirin, the improvement of angina pectoris after treatment, adverse effects during treatment and the efficacy of treatment were analyzed.Compared with the control group, the observation group had significant treatment effect on duration of angina pectoris, improvement of number of attacks and the effective rate of treatment, and there was significant difference between the two groups (P<0.05).There were no significant adverse events during the treatment period of two group patients.Results showed that the use of clopidogrel combined with aspirin on patients with unstable angina can improve the symptoms of angina in a short time, reduce the intake of nitroglycerin, which is a preferred way to treat unstable angina and is worthy of further promotion.%以2015年10月-2016年10月我院收治的100例UA患者为研究对象,将病患随机平均分为2组,每组50例.对照组患者使用阿司匹林治疗,观察组患者使用氯吡格雷联合阿司匹林治疗,分析治疗后患者心绞痛改善情况,治疗期间不良反应和治疗有效率.相较于对照组,观察组病患在心绞痛持续时长,发作次数改善情况,治疗有效率方面显著较好,组间数据存在显著差异,P<0.05.两组患者在治疗期间内未发生显著不良反应.结论:对于不稳定型心绞痛者,使用氯吡格雷联合阿司匹林治疗,安全性强,临床效果好,可在短时间内改善患者的心绞痛症状,减少硝酸甘油服用次数,不失为一种治疗UA的首选方式,值得进一步推广.

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