Process for removing bile salts from a patient and compositions therefor
申请(专利)号:
US19970959471
申请日期:
1997-10-28
公开/公告号:
US5840766A
公开/公告日期:
1998-11-24
申请(专利权)人:
GELTEX PHARMACEUTICALS, INC.
摘要:
A method for removing bile salts from a patient by ion exchange by administering to the patient a therapeutically effective amount of one or more highly crosslinked polymers characterized by a repeat unit having the formula ##STR1## or copolymer thereof, where n is an integer; R.sup.1 is H or a C.sub.1 -C.sub.8 alkyl group: M is ##STR2## Z is O, NR. sup.3, S, or (CH.sub.2).sub.m ; m=0-10; R.sup.3 is H or a C. sub.1 -C.sub. 8 alkyl group; and R.sup.2 is ##STR3## where p=0-10, and each R.sup.4, R. sup.5, and R.sup.6, independently, is H, a C.sub.1 -C. sub.8 alkyl group, or an aryl group.
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