摘要：

Total syntheses of macrosphelides published up to August, 2004 are described in the following order : (1) lactonization at the three possible ester linkages; (2) interconversion between macrosphelides A and B; (3) preparation of the segments and the total synthesis via lactonization; (4) the synthesis based on the furan ring cleavage reaction to furnish 4-oxo-2-alkenoic acids; (5) the syntheses through metathesis and carbonylation.

展开