IN VITRO SYNTHESIS OF A LAYERED CELL SORTED TISSUE
申请(专利)号：
WO2001US47928
申请日期：
2001-12-07
公开/公告号：
WO0246375A1
公开/公告日期：
2002-06-13
申请(专利权)人：
XGENE CORPORATION;HOEFFLER, WARREN, K.;FINLAY, DEBORAH
被引量：
摘要：
The present invention relates to a layered cell sorted tissue that is formed in vitro. The tissue is generated by the spontaneous sorting of cells from a homogenous cell mixture into discrete layers by cell type. Connective tissue components, tissue components, such as fibronectin, may be used to manipulate orientation of the layers during the cell sorting process. The layered cell sorted tissue may be used as a skin graft for burns, wounds, and ulcers. The tissue may also be used in assays to determine effects of chemicals or drugs on human tissue in vitro as well as provide an in vitro assay for tumor cell metastasis.
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