Cisplatin Toxicity in Dorsal Root Ganglion Neurons Is Relieved by Meclizine via Diminution of Mitochondrial Compromise and Improved Clearance of DNA Damage
摘要：
Chemotherapy-induced neurotoxicity of peripheral nervous system (PNS) hinders efficacy of cancer treatments. Mechanisms initiating PNS injury by anticancer drugs are incompletely understood delaying...
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关键词：
Cisplatin DNA damage DNA repair Dorsal root ganglion neurons Meclizine Mitochondrial respiration mtDNA Pentose phosphate pathway ROS
DOI：
10.1007/s12035-016-0273-9
被引量：
年份：
2017
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