Clinical Trials: A Practical Approach

This comprehensive, unified text on the principles and practice of clinical trials presents a detailed account of how to conduct the trials. It describes t...

ID Hill，SJ Pocock - 《Journal of the Royal Society of Medicine》

Nitrous oxide analgesia: a psychophysical evaluation using verbal descriptor scaling.

The effect of 33% nitrous oxide/67% oxygen was compared with 100% oxygen and air on verbal reports of either sensory intensity or unpleasantness of sensati...

MW Heft，RH Gracely，R Dubner - 《Journal of Dental Research》

Amitriptyline relieves diabetic neuropathy pain in patients with normal or depressed mood

In a randomized, double-blind crossover study, 29 patients with painful diabetic neuropathy received 6 weeks of amitriptyline and 6 weeks of an "active" pl...

MB Max，M Culnane，SC Schafer，... - 《Neurology》

A Flood of Opioids, a Rising Tide of Deaths

In a randomized, double-blind crossover study, 29 patients with painful diabetic neuropathy received 6 weeks of amitriptyline and 6 weeks of an "active" pl...

AJ Hall

Amitriptyline versus placebo in postherpetic neuralgia

To study the effects of amitriptyline in treating postherpetic neuralgia, 24 patients were randomly assigned to either drug or placebo in a double-blind cr...

CPN Watson，RJ Evans，K Reid，... - 《Pain》

Dubner R, Bennett GJ. Spinal and trigeminal mechanisms of nociception

Dubner R, Bennett GJ.

R Dubner，GJ Bennett - 《Annual Review of Neuroscience》

Amitriptyline versus placebo in post-herpetic neuralgia

Dubner R, Bennett GJ.

PN C.，Watson，and，... - 《Pain》

Clinical trial of carbazepine (tegretol) in trigeminal neuralgia.

No abstract available.

FG Campbell，JG Graham，KJ Zilkha - 《J Neurol Neurosurg Psychiatry》

Chronic effects of fluoxetine, a selective inhibitor of serotonin uptake, on neurotransmitter receptors

Fluoxetine administration to rats at a dose of 10 mg/kg i.p. daily up to 12 or 24 days failed to change the concentration-dependent binding of [ 3 H]WB4101...

DT Wong，LR Reid，FP Bymaster，... - 《Journal of Neural Transmission》

Factors influencing Clinical Evaluation of Drugs with special reference to the Double-Blind Technique. [Report to the Council on Drugs (Kautz, H. D., Secre...

The forces which may influence data in clinical evaluations of drugs are as follows: -(1) Pharmaco-dynamic actions, the measurement of which is particularl...

W Modell，RW Houde - 《Journal of the American Medical Association》