Recovery of hepatocellular ATP and "pericentral apoptosis" after hemorrhage and resuscitation
摘要：
Ischemia and reperfusion result in a hepatocellular stress gene response, characterized by a zonal heterogeneity with pericentral hepatocytes being the primary target. In the present study, we assessed cell type-specific and zonal pattern of activation of redox-sensitive transcription factors nuclear factor-kappaB (NFkappaB) and activator protein-1 (AP-1) in a graded model of hemorrhage and...
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DOI：
10.1096/fj.02-0624com
被引量：
年份：
2003
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