Granulation process
申请(专利)号:
SE20020000539
申请日期:
2002-02-25
公开/公告号:
SE0200539D0
公开/公告日期:
2002-02-25
申请(专利权)人:
METCON MEDICIN AB
被引量:
摘要:
A process for the manufacture of a corn starch granulate possessing resistance to enzymatic degradation upon oral administration, comprising the steps: a) granulating native corn starch by cautious mixing of a granulation fluid comprising methyl cellulose or ethyl cellulose as a binder, ethanol or water as a solvent, corn starch and a sweetener, b) subjecting the granulated material resulting from step a) to wet sieving; c) drying the granulate obtained in step b) at a temperature less than about 55° C. to avoid gelatinization of the corn starch; and d) sizing the dried granulate from step c) by dry sieving. A corn starch granulate and a corn starch granulate tablet also are provided.
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