Granulation process

阅读量:

69

申请(专利)号:

SE20020000539

申请日期:

2002-02-25

公开/公告号:

SE0200539D0

公开/公告日期:

2002-02-25

申请(专利权)人:

METCON MEDICIN AB

发明人:

H HanssonE Lindner-Olsson

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被引量:

381

摘要:

A process for the manufacture of a corn starch granulate possessing resistance to enzymatic degradation upon oral administration, comprising the steps: a) granulating native corn starch by cautious mixing of a granulation fluid comprising methyl cellulose or ethyl cellulose as a binder, ethanol or water as a solvent, corn starch and a sweetener, b) subjecting the granulated material resulting from step a) to wet sieving; c) drying the granulate obtained in step b) at a temperature less than about 55° C. to avoid gelatinization of the corn starch; and d) sizing the dried granulate from step c) by dry sieving. A corn starch granulate and a corn starch granulate tablet also are provided.

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2009
被引量:41

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